CD226 deficiency improves cognitive functions and ameliorates anxiety-like behaviors in mice

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CD226 deficiency improves cognitive functions and ameliorates anxiety‐like behaviors in mice

Background CD226 is a cell surface adhesion molecule expressed in the immune system and central nervous system. Although the role of CD226 in the function of immune cells has been well studied, there has been no report on the potential functional significance of CD226 in neural cells. Methods We investigated the role of CD226 on the cognitive function and behaviors using CD226 knockout (CD226...

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ژورنال

عنوان ژورنال: Brain and Behavior

سال: 2017

ISSN: 2162-3279

DOI: 10.1002/brb3.871